Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129929 | 0.88 | NR4A2 (0.41) | POLBAAK1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11113410 | 0.80 | SMN1; SMN2 (0.46) | AAK1ALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL25907970 | 0.79 | AAK1 (0.50) | AAK1ALDH1A1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL16446063 | 0.78 | AAK1 (0.39) | POLBAAK1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11117263 | 0.78 | ALDH1A1 (0.38) | POLBAAK1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11108549 | 0.77 | AAK1 (0.44) | POLBAAK1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11116305 | 0.76 | PMP22 (0.45) | POLBAAK1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL11116348 | 0.76 | PMP22 (0.45) | POLBAAK1ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL16446183 | 0.76 | AAK1 (0.35) | POLBAAK1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11116333 | 0.73 | AAK1 (0.41) | POLBAAK1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58000955-A | — | — | None | — | — | JP | disclosed |
| EP-0047516-B1 | PROPYLAMINE DERIVATIVE AND PROCESS OF MANUFACTURING THE SAME | TORAY INDUSTRIES, INC. (JP) | 1984-01-04 | — | — | EP | disclosed |
| JP-S58955-A | PREPARATION OF BUTYRIC ACID DERIVATIVE | TORAY IND INC | 1983-01-06 | — | — | JP | disclosed |
| EP-0047516-A1 | Propylamine derivative and process of manufacturing the same | TORAY INDUSTRIES, INC. (JP) | 1982-03-17 | — | — | EP | disclosed |