Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 6/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113410 | 0.84 | SMN1; SMN2 (0.46) | AAK1ALDH1A1TSHRTDP1SMN1; SMN2 | |
| SCHEMBL16116897 | 0.82 | AAK1 (0.54) | AAK1CTSKALDH1A1TSHRHSD17B10 | |
| SCHEMBL11129929 | 0.81 | NR4A2 (0.41) | AAK1ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL11112239 | 0.79 | POLB (0.37) | AAK1CTSKALDH1A1TSHRHSD17B10 | |
| SCHEMBL24696988 | 0.79 | AAK1 (0.57) | AAK1CTSKALDH1A1TSHRHSD17B10 | |
| SCHEMBL25907951 | 0.78 | AAK1 (0.62) | AAK1CTSKALDH1A1P2RY12SMN1; SMN2 | |
| SCHEMBL28964326 | 0.76 | AAK1 (0.51) | AAK1CTSSCTSKALDH1A1TSHR | |
| SCHEMBL16446063 | 0.75 | AAK1 (0.39) | AAK1ALDH1A1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL9026259 | 0.74 | L3MBTL1 (0.49) | AAK1 | |
| SCHEMBL22754527 | 0.72 | AAK1 (0.70) | AAK1CTSKALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912644-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | CELGENE CORPORATION (US) | 2024-02-27 | — | — | US | disclosed |
| US-20230234914-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | CELGENE CORPORATION | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234914-A1 | PROCESSES FOR THE PREPARATION OF (S)-TERT-BUTYL 4,5-DIAMINO-5-OXOPENTANOATE | UMPS, DHPS, NT5C3B | AAK1 3188/4885CTSS 3691/4885CTSK 4660/4885 |
| US-11912644-B2 | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate | UMPS, DHPS, NT5C3B | AAK1 3188/4885CTSS 3691/4885CTSK 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.