Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116141 | 0.87 | ACACB (0.41) | ACACBMMP1MMP2MMP3ATM | |
| SCHEMBL11114098 | 0.82 | HRH3 (0.50) | — | |
| SCHEMBL11113046 | 0.82 | HRH3 (0.50) | — | |
| SCHEMBL11120268 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ATMKDM4E | |
| SCHEMBL11118198 | 0.78 | HRH3 (0.46) | — | |
| SCHEMBL11113049 | 0.77 | ACACB (0.43) | ACACB | |
| SCHEMBL11118618 | 0.76 | DRD3 (0.53) | — | |
| SCHEMBL11118107 | 0.74 | DRD3 (0.64) | — | |
| SCHEMBL11114775 | 0.74 | DRD3 (0.51) | — | |
| Hydrochloric Acid SCHEMBL11114697 | 0.74 | DRD3 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |