Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.50 |
| ▸ | CCR3 | P51677 | 5/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113046 | 1.00 | HRH3 (0.50) | HRH3CCR3LTA4HTP53CYP1A2 | |
| SCHEMBL11118198 | 0.96 | HRH3 (0.46) | HRH3CCR3TP53CYP1A2CYP3A4 | |
| SCHEMBL11118618 | 0.86 | DRD3 (0.53) | — | |
| SCHEMBL11115212 | 0.85 | DRD3 (0.61) | — | |
| SCHEMBL11114775 | 0.84 | DRD3 (0.51) | — | |
| Hydrochloric Acid SCHEMBL11114697 | 0.84 | DRD3 (0.60) | — | |
| SCHEMBL11112280 | 0.82 | ACACB (0.41) | — | |
| SCHEMBL11118776 | 0.82 | HRH3 (0.47) | HRH3CYP2D6ACHESMAD3 | |
| SCHEMBL11118107 | 0.82 | DRD3 (0.64) | — | |
| SCHEMBL11118840 | 0.79 | DRD2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |