Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1530292 | 0.73 | ALDH1A1 (0.44) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL28690512 | 0.72 | BLM (0.49) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL29521900 | 0.72 | BLM (0.49) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL427855 | 0.72 | BLM (0.49) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL12679276 | 0.72 | BLM (0.49) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL427854 | 0.72 | BLM (0.49) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL19873299 | 0.70 | RIPK1 (0.43) | ALDH1A1IDO1SMN1; SMN2HIF1AKMT2A | |
| SCHEMBL29009853 | 0.70 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL28798055 | 0.68 | RIPK1 (0.47) | ALDH1A1HIF1AKMT2AMEN1KDM4E | |
| SCHEMBL17931647 | 0.68 | RIPK1 (0.51) | ALDH1A1HIF1AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450159-A | ORGAN TRANSPLANTS; IMMUNOLOGY | THE UPJOHN COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| US-4352929-A | ANTIBODY INHIBITORS | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | disclosed |