Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107638 | 0.89 | ALDH1A1 (0.59) | TBXAS1TBXA2RALDH1A1S1PR1S1PR3 | |
| SCHEMBL11105772 | 0.86 | RARB (0.57) | TBXAS1TBXA2RALDH1A1MAPT | |
| SCHEMBL11104594 | 0.85 | CYP4F2 (0.51) | TBXAS1TBXA2RALDH1A1 | |
| SCHEMBL11403900 | 0.84 | SMN1; SMN2 (0.48) | TBXAS1TBXA2RALDH1A1 | |
| SCHEMBL11332902 | 0.84 | TBXA2R (0.58) | TBXAS1TBXA2R | |
| SCHEMBL11332214 | 0.84 | TBXA2R (0.58) | TBXAS1TBXA2R | |
| SCHEMBL11101691 | 0.81 | KDM4E (0.48) | TBXAS1TBXA2RALDH1A1 | |
| SCHEMBL11101726 | 0.81 | KDM4E (0.48) | TBXAS1TBXA2RALDH1A1 | |
| SCHEMBL7824985 | 0.81 | RELA (0.51) | FFAR1FFAR4ALDH1A1 | |
| SCHEMBL6578156 | 0.81 | RELA (0.51) | FFAR1FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443477-A | ANTICOAGULANTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-17 | — | — | US | disclosed |
| EP-0031954-A2 | Sulphonamides, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-07-15 | — | — | EP | disclosed |