Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 4/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665996 | 0.81 | CA1 (0.61) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL31196532 | 0.80 | CA1 (0.59) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL17099935 | 0.80 | CA1 (0.59) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL11705060 | 0.78 | MAPT (0.79) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL8717056 | 0.78 | PLK1 (0.80) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL837307 | 0.76 | PLK1 (1.00) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL942259 | 0.76 | CA1 (1.00) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL28932612 | 0.76 | CA1 (0.57) | CA1CA2PLK1NPC1RAB9A | |
| SCHEMBL5803581 | 0.76 | HDAC1 (0.60) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8573562 | 0.75 | CA1 (0.68) | CA1CA2PLK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103445-A2 | Process for production of prostaglandins E or F, and novel 7-(thiocarbo-acyloxy) prostaglandins E or F | TEIJIN LIMITED (JP) | 1984-03-21 | — | — | EP | disclosed |