Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.35 |
| ▸ | HTR2B | P41595 | 5/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113079 | 0.85 | AR (0.45) | HTR2AARPOLBHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL11112345 | 0.84 | AR (0.44) | HTR2AARPOLBHTR2CHTR2B | |
| SCHEMBL11105016 | 0.82 | HTR2A (0.50) | HTR2AARRETHTR2CSTK17B | |
| SCHEMBL11105723 | 0.82 | HTR2C (0.38) | HTR2AHTR2CHTR2BSLC6A4STK17B | |
| SCHEMBL11112779 | 0.80 | APEX1 (0.50) | RETKDRSTK17B | |
| SCHEMBL11109901 | 0.78 | HTR2A (0.43) | HTR2AARMAPK1GPR3 | |
| SCHEMBL11113392 | 0.78 | HTR2A (0.33) | HTR2AARPOLBRETKDR | |
| SCHEMBL11108825 | 0.78 | HTT (0.40) | ARRETKDRSTK17B | |
| SCHEMBL11105864 | 0.77 | KDM4E (0.42) | HTR2AARHTR2CHTR2BCHRM2 | |
| SCHEMBL11103990 | 0.77 | ALDH1A1 (0.38) | ARRETKDRSTK17B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |