Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALPL | P05186 | 2/20 | 0.55 |
| ▸ | ALPI | P09923 | 2/20 | 0.55 |
| ▸ | ALPG | P10696 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489196 | 0.94 | POLB (0.56) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL12224103 | 0.87 | HPGD (0.62) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL27450929 | 0.79 | CSNK1D (0.46) | HPGDKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7748285 | 0.79 | HPGD (0.63) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL1433698 | 0.78 | RAB9A (0.81) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL11162047 | 0.78 | KMT2A (0.61) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL8695093 | 0.77 | MAPT (0.82) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL27363616 | 0.76 | KMT2A (0.55) | HPGDKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11775788 | 0.76 | KMT2A (0.69) | HPGDKMT2AALPLALPIALPG | |
| SCHEMBL7890148 | 0.76 | NPC1 (0.63) | HPGDKMT2AALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470997-A | Esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4423070-A | DI- AND TRIESTERS OF N-(ACYLAMINOALKYL)-DIHYDROXYPHENYLETHANOLAMINES, ANTIINFLAMMATORY | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-12-27 | — | — | US | disclosed |
| US-4355045-A | Anti-inflammatory 1-phenylethanolamine derivatives pharmaceutical compositions thereof and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-10-19 | — | — | US | disclosed |
| EP-0000809-B1 | ANTI-INFLAMMATORY 1-PHENYLETHANOLAMINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-04-14 | — | — | EP | disclosed |
| EP-0000809-A1 | Anti-inflammatory 1-phenylethanolamine derivatives, pharmaceutical compositions thereof and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-02-21 | — | — | EP | disclosed |