SCHEMBL1433698

SCHEMBL1433698

CCNC(=O)COc1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.81
SMN1; SMN2 Q16637 2/20 0.81
NPC1 O15118 2/20 0.81
KMT2A Q03164 3/20 0.67
HPGD P15428 3/20 0.67
HTT P42858 2/20 0.65
KDM4E B2RXH2 1/20 0.61
TSHR P16473 1/20 0.61
RECQL P46063 1/20 0.61
MEN1 O00255 2/20 0.60
CYP1A2 P05177 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
ALPL P05186 1/20 0.59
ALPI P09923 1/20 0.59
ALPG P10696 1/20 0.59
USP2 O75604 1/20 0.58
POLB P06746 1/20 0.57
PKM P14618 1/20 0.57
PTPN1 P18031 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17921354 0.86 RAB9A (0.63) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL10475269 0.86 RECQL (0.71) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL19002729 0.84 RAB9A (0.69) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL13673100 0.84 RAB9A (0.69) RAB9ASMN1; SMN2NPC1HPGDHTT
SCHEMBL11775788 0.83 KMT2A (0.69) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL4860148 0.83 RECQL (0.81) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL19002731 0.82 RAB9A (0.67) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL4053405 0.82 RAB9A (0.67) RAB9ASMN1; SMN2NPC1HPGDHTT
SCHEMBL7748285 0.82 HPGD (0.63) RAB9ASMN1; SMN2NPC1KMT2AHPGD
SCHEMBL27754995 0.82 RAB9A (0.67) RAB9ASMN1; SMN2NPC1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291171-B Synergistic lubricating oil composition containing mixture of olefin copolymer dispersant type viscosity improver and amine compound 雪佛龙奥伦耐有限责任公司 2022-02-01 CN disclosed
EP-3405554-B1 LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND CHEVRON ORONITE CO (US) 2019-12-25 EP disclosed
US-10414999-B2 Synergistic lubricating oil composition containing a mixture of olefin copolymer dispersant-type viscosity improver and amine compound CHEVRON ORONITE COMPANY LLC (US) 2019-09-17 US disclosed
EP-3405554-A1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND Chevron Oronite Company LLC (US) 2018-11-28 EP disclosed
EP-2875105-B1 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND AN ARYLOXYALYLKENE MONOAMINE CHEVRON ORONITE CO (US) 2018-01-03 EP disclosed
US-20170231962-A1 Compound Combinations for Attenuation of Bacterial Virulence NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-08-17 US disclosed
WO-2017127637-A1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND CHEVRON ORONITE COMPANY LLC (US) 2017-07-27 WO disclosed
US-20170211011-A1 SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF OLEFIN COPOLYMER DISPERSANT-TYPE VISCOSITY IMPROVER AND AMINE COMPOUND CHEVRON ORONITE COMPANY LLC 2017-07-27 US disclosed
US-9115237-B2 Viscosity improver grafted with unsaturated acylating agent and an aryloxyalylkene monoamine CHEVRON ORONITE COMPANY LLC (US) 2015-08-25 US disclosed
EP-2875105-A1 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND AN ARYLOXYALYLKENE MONOAMINE Chevron Oronite Company LLC (US) 2015-05-27 EP disclosed
US-8841306-B2 Antimicrobials PANACEA BIOTEC LTD. (IN) 2014-09-23 US disclosed
WO-2014014561-A1 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND AN ARYLOXYALYLKENE MONOAMINE CHEVRON ORONITE COMPANY LLC (US) 2014-01-23 WO disclosed
US-20140024567-A1 VISCOSITY IMPROVER GRAFTED WITH UNSATURATED ACYLATING AGENT AND AN ARYLOXYALYLKENE MONOAMINE CHEVRON ORONITE COMPANY LLC (US) 2014-01-23 US disclosed
US-8268885-B2 Entry inhibitors of the HIV virus JANSSEN R&D IRELAND (IE) 2012-09-18 US disclosed
US-8268885-B2 Entry inhibitors of the HIV virus JANSSEN R&D IRELAND (IE) 2012-09-18 US disclosed
EP-2300430-A1 BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR R-Tech Ueno, Ltd. (JP) 2011-03-30 EP disclosed
WO-2010058423-A2 NOVEL ANTIMICROBIALS PANACEA BIOTEC LTD. (IN) 2010-05-27 WO disclosed
US-5276192-A Preparation of phenoxyethanamines TEXACO CHEMICAL COMPANY (US) 1994-01-04 US disclosed
CN-1034918-A Chemical compound ICI PLC (GB) 1989-08-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170231962-A1 Compound Combinations for Attenuation of Bacterial Virulence PNISR, PGLS, QRFPR RAB9A 127/4885SMN1; SMN2 4813/4885NPC1 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.