Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500113 | 0.77 | SCN4A (0.39) | SCN4ALMNAOPRM1 | |
| SCHEMBL11116317 | 0.77 | SCN4A (0.39) | SCN4ALMNAOPRM1 | |
| SCHEMBL11115485 | 0.77 | SCN4A (0.34) | SCN4ALMNAOPRM1 | |
| SCHEMBL11118999 | 0.75 | SCN4A (0.37) | SCN4ALMNAOPRM1 | |
| SCHEMBL11117599 | 0.72 | LMNA (0.43) | SCN4ALMNAOPRM1 | |
| SCHEMBL11115188 | 0.72 | SCN4A (0.39) | SCN4AMEN1LMNAMAPTHTT | |
| SCHEMBL11116061 | 0.72 | SCN4A (0.40) | SCN4ALMNAOPRM1 | |
| SCHEMBL11121131 | 0.72 | IKZF2 (0.37) | SCN4AOPRM1 | |
| SCHEMBL11119013 | 0.71 | MEN1 (0.38) | SCN4AMEN1KMT2AOPRM1 | |
| SCHEMBL11119011 | 0.71 | SCN4A (0.36) | SCN4ALMNAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |