Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111207 | 0.92 | SCN4A (0.39) | LMNASCN4AOPRM1NPC1SLC6A2 | |
| SCHEMBL11116215 | 0.92 | SCN4A (0.39) | LMNASCN4AOPRM1NPC1SLC6A2 | |
| SCHEMBL11113548 | 0.91 | SCN4A (0.39) | LMNASCN4AOPRM1HTR2C | |
| SCHEMBL11116061 | 0.87 | SCN4A (0.40) | LMNASCN4AOPRM1HTR2C | |
| SCHEMBL10500113 | 0.86 | SCN4A (0.39) | LMNASCN4AOPRM1 | |
| SCHEMBL11116317 | 0.86 | SCN4A (0.39) | LMNASCN4AOPRM1 | |
| SCHEMBL11113500 | 0.85 | LMNA (0.43) | LMNASCN4AOPRM1SLC6A2SLC6A4 | |
| SCHEMBL11115188 | 0.85 | SCN4A (0.39) | LMNASCN4AOPRM1 | |
| SCHEMBL11117393 | 0.85 | SCN4A (0.39) | LMNASCN4AOPRM1 | |
| SCHEMBL11118999 | 0.83 | SCN4A (0.37) | LMNASCN4AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |