Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117599 | 0.91 | LMNA (0.43) | SCN4AOPRM1LMNAHTR2C | |
| SCHEMBL11111207 | 0.89 | SCN4A (0.39) | SCN4AOPRM1LMNAHTR2C | |
| SCHEMBL11116215 | 0.89 | SCN4A (0.39) | SCN4AOPRM1LMNAHTR2C | |
| SCHEMBL10500113 | 0.82 | SCN4A (0.39) | SCN4AOPRM1LMNA | |
| SCHEMBL11116317 | 0.82 | SCN4A (0.39) | SCN4AOPRM1LMNA | |
| SCHEMBL11116061 | 0.81 | SCN4A (0.40) | SCN4AOPRM1LMNAHTR2CHSD11B1 | |
| SCHEMBL11115188 | 0.79 | SCN4A (0.39) | SCN4AOPRM1LMNA | |
| SCHEMBL11117393 | 0.79 | SCN4A (0.39) | SCN4AOPRM1LMNA | |
| SCHEMBL11118999 | 0.78 | SCN4A (0.37) | SCN4AOPRM1LMNA | |
| SCHEMBL11113500 | 0.77 | LMNA (0.43) | SCN4AOPRM1LMNAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |