Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968152 | 0.77 | TSHR (0.47) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18210642 | 0.76 | FDPS (0.42) | EGLN3CYP3A4CYP2C19KMT2AFDPS | |
| SCHEMBL3240872 | 0.74 | EGLN3 (0.44) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5746694 | 0.74 | — | — | |
| SCHEMBL5899076 | 0.73 | EGLN3 (0.55) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10816033 | 0.72 | EGLN3 (0.43) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12057496 | 0.72 | CYP1A2 (0.51) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11096568 | 0.72 | EGLN3 (0.47) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10729444 | 0.71 | EGLN3 (0.42) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10363553 | 0.71 | MEN1 (0.46) | EGLN3CYP3A4CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0102163-A1 | Triazole derivatives and compositions containing the same | CHEVRON RESEARCH COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |