Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 16/20 | 1.00 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SCN4A | P35499 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412073 | 0.81 | P2RX4 (0.71) | P2RX4BCHELMNATSHRMAPK1 | |
| SCHEMBL18415539 | 0.81 | P2RX4 (0.69) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL7980250 | 0.78 | P2RX4 (0.67) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL1572434 | 0.77 | P2RX4 (0.62) | P2RX4BCHELMNATSHRMAPK1 | |
| SCHEMBL12436609 | 0.77 | P2RX4 (0.62) | P2RX4BCHELMNATSHRMAPK1 | |
| SCHEMBL13051502 | 0.77 | BCHE (0.68) | P2RX4BCHEP2RX1P2RX3P2RX7 | |
| SCHEMBL11113845 | 0.77 | P2RX4 (0.67) | P2RX4BCHELMNATSHRMAPK1 | |
| SCHEMBL8739119 | 0.76 | BCHE (1.00) | P2RX4BCHELMNASMN1; SMN2 | |
| SCHEMBL220840 | 0.75 | P2RX4 (0.59) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL15603438 | 0.74 | P2RX4 (0.66) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185443-A | Method for preparing 5-carbamoyl-5H-dibenz[b,f]azepine | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1993-02-09 | — | — | US | disclosed |