Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 11/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112161 | 0.84 | BCHE (0.49) | BCHEACHEP2RX4P2RX1P2RX3 | |
| SCHEMBL11113522 | 0.81 | P2RX4 (0.45) | P2RX4MAPTKMT2AALDH1A1P2RX1 | |
| SCHEMBL11111113 | 0.81 | LMNA (0.59) | BCHEACHEP2RX4MAPTKMT2A | |
| SCHEMBL11118498 | 0.81 | BCHE (0.47) | BCHEACHEP2RX4MAPTKMT2A | |
| SCHEMBL11109304 | 0.80 | BCHE (0.46) | BCHEACHEP2RX4P2RX1P2RX3 | |
| SCHEMBL11113845 | 0.79 | P2RX4 (0.67) | BCHEACHEP2RX4P2RX1P2RX3 | |
| SCHEMBL18522349 | 0.76 | SMN1; SMN2 (0.40) | BCHEACHEMAPTKMT2AKDM4E | |
| SCHEMBL10655660 | 0.71 | CES1 (0.67) | BCHEACHEMAPTKMT2AALDH1A1 | |
| SCHEMBL11358923 | 0.71 | ASAH1 (0.54) | BCHEACHEMAPTKDM4EALDH1A1 | |
| SCHEMBL12459415 | 0.70 | GPR84 (0.54) | MAPTKMT2AKDM4EALDH1A1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | claimed |
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |