Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10938889 | 0.91 | ESR1 (0.44) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29332572 | 0.90 | ESR1 (0.43) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10658289 | 0.84 | KMT2A (0.40) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL5801159 | 0.79 | KDM4E (0.47) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4164624 | 0.79 | KDM4E (0.47) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3586530 | 0.78 | ALDH1A1 (0.51) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4155032 | 0.77 | KDM4E (0.45) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11692389 | 0.77 | KDM4E (0.53) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4802959 | 0.76 | KDM4E (0.45) | ESR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL10662082 | 0.76 | KMT2A (0.38) | MEN1KMT2AALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447358-A | FOR POLYAMIDE AND WOOL TEXTILE DYEING | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |