Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 16/20 | 0.77 |
| ▸ | FAAH | O00519 | 8/20 | 0.77 |
| ▸ | DRD2 | P14416 | 13/20 | 0.68 |
| ▸ | DRD4 | P21917 | 6/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR2C | P28335 | 2/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116160 | 0.97 | DRD3 (0.77) | DRD3FAAHDRD2DRD4KCNH2 | |
| Hydrochloric Acid SCHEMBL11114915 | 0.91 | DRD3 (0.68) | DRD3FAAHDRD2DRD4HTR1A | |
| SCHEMBL11118155 | 0.90 | DRD3 (0.65) | DRD3FAAHDRD2DRD4HTR1A | |
| SCHEMBL16406402 | 0.87 | DRD3 (1.00) | DRD3FAAHDRD2DRD4KCNH2 | |
| Hydrochloric Acid SCHEMBL17889741 | 0.86 | DRD3 (1.00) | DRD3FAAHDRD2DRD4KCNH2 | |
| SCHEMBL11114880 | 0.86 | DRD3 (0.62) | DRD3FAAHDRD2DRD4HTR1A | |
| SCHEMBL11114077 | 0.84 | DRD3 (0.61) | DRD3FAAHDRD2DRD4SLC6A2 | |
| SCHEMBL16406382 | 0.84 | DRD3 (1.00) | DRD3FAAHDRD2DRD4KCNH2 | |
| SCHEMBL11116794 | 0.84 | DRD2 (0.56) | DRD3FAAHDRD2DRD4HTR1A | |
| Hydrochloric Acid SCHEMBL16400254 | 0.83 | DRD3 (1.00) | DRD3FAAHDRD2DRD4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |