Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | DRD3 | P35462 | 9/20 | 0.55 |
| ▸ | FAAH | O00519 | 7/20 | 0.55 |
| ▸ | DRD4 | P21917 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118155 | 0.86 | DRD3 (0.65) | DRD2HTR1ADRD3FAAHDRD4 | |
| SCHEMBL11114880 | 0.85 | DRD3 (0.62) | DRD2HTR1ADRD3FAAHDRD4 | |
| Hydrochloric Acid SCHEMBL11114915 | 0.85 | DRD3 (0.68) | DRD2HTR1ADRD3FAAHDRD4 | |
| SCHEMBL11116160 | 0.84 | DRD3 (0.77) | DRD2HTR1AADRA1ADRD3FAAH | |
| SCHEMBL11114077 | 0.84 | DRD3 (0.61) | DRD2ADRA1ADRD3FAAHDRD4 | |
| SCHEMBL11113965 | 0.84 | DRD3 (0.77) | DRD2HTR1ADRD3FAAHDRD4 | |
| SCHEMBL11115212 | 0.73 | DRD3 (0.61) | DRD2HTR1AADRA1ADRD3FAAH | |
| SCHEMBL11118107 | 0.73 | DRD3 (0.64) | DRD2HTR1AADRA1ADRD3FAAH | |
| Hydrochloric Acid SCHEMBL11114697 | 0.73 | DRD3 (0.60) | DRD2HTR1AADRA1ADRD3FAAH | |
| SCHEMBL11116644 | 0.72 | DRD3 (0.64) | DRD2HTR1AADRA1ADRD3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |
| EP-0122197-A2 | Anchoring devices for lubricated prestressing reinforcements | FREYSSINET INTERNATIONAL (STUP) (FR) | 1984-10-17 | — | — | EP | disclosed |