⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31171066 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL4416814 | 0.97 | — | — | |
| SCHEMBL2757245 | 0.80 | NPC1 (0.50) | — | |
| SCHEMBL17664105 | 0.79 | MEN1 (0.40) | — | |
| SCHEMBL29911912 | 0.77 | — | — | |
| SCHEMBL9340375 | 0.75 | P2RX3 (0.50) | — | |
| SCHEMBL31030 | 0.71 | — | — | |
| SCHEMBL17800 | 0.71 | — | — | |
| SCHEMBL676678 | 0.71 | HPGDS (0.56) | — | |
| SCHEMBL10765894 | 0.71 | HDAC6 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083897-A1 | GCN2 MODULATING COMPOUNDS AND USES THEREOF | HIBERCELL, INC. | 2024-03-14 | — | — | US | claimed |
| US-20230192657-A1 | 1,2,4-TRIAZOLINONE CB1 INHIBITORS | GFB (ABC), LLC | 2023-06-22 | — | — | US | claimed |
| EP-4114838-A1 | 1,2,4-TRIAZOLINONE CB1 INHIBITORS | Goldfinch Bio, Inc. (US) | 2023-01-11 | — | — | EP | claimed |
| CN-113603690-B | (E) -acrylic acid derivative containing xanthine-8-group and preparation method and application thereof | 南开大学 | 2022-10-25 | — | — | CN | claimed |
| CN-114727983-A | Xanthine CB1 inhibitors | 金翅雀生物公司 | 2022-07-08 | — | — | CN | claimed |
| CN-113603690-A | (E) -acrylic acid derivative containing xanthine-8-group and preparation method and application thereof | 南开大学 | 2021-11-05 | — | — | CN | claimed |
| US-11001564-B2 | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-05-11 | — | — | US | claimed |
| WO-2021062089-A1 | XANTHINE CB1 INHIBITORS | GOLDFINCH BIO, INC. (US) | 2021-04-01 | — | — | WO | claimed |
| US-20190225593-A1 | SUBSTITUTED CHROMANE-8-CARBOXAMIDE COMPOUNDS AND ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (CA) | 2019-07-25 | — | — | US | claimed |
| EP-3089980-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2018-01-31 | — | — | EP | claimed |
| US-8329739-B2 | Phenylimidazole compounds | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2012-12-11 | — | — | US | claimed |
| CN-102307861-A | Phenylimidazole compounds | OTSUKA PHARMA CO LTD (JP) | 2012-01-04 | — | — | CN | claimed |
| EP-2394996-A1 | PHENYLIMIDAZOLE COMPOUNDS | Otsuka Pharmaceutical Factory, Inc. (JP) | 2011-12-14 | — | — | EP | claimed |
| US-20110275823-A1 | PHENYLIMIDAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2011-11-10 | — | — | US | claimed |
| US-20100227844-A1 | CANNABINOID-1 RECEPTOR MODULATORS USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME CORP. | 2010-09-09 | — | — | US | claimed |
| US-20090118286-A1 | Heterobicyclic Acrylamides | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | US | claimed |
| WO-2009054929-A1 | CANNABINOID-1 RECEPTOR MODULATORS USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2009-04-30 | — | — | WO | claimed |
| EP-1858899-A1 | HETEROBICYCLIC ACRYLAMIDES | Bayer CropScience AG (DE) | 2007-11-28 | — | — | EP | claimed |
| WO-2006094666-A1 | HETEROBICYCLIC ACRYLAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-09-14 | — | — | WO | claimed |
| WO-2004048317-A1 | SUBSTITUTED AMIDES ACTIVE AT THE CANNABINOID-1 RECEPTOR | MERCK & CO., INC. (US) | 2004-06-10 | — | — | WO | claimed |