Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116583 | 0.97 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ARAD52KDM4E | |
| SCHEMBL11008698 | 0.96 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ARAD52KDM4E | |
| SCHEMBL10376145 | 0.82 | POLB (0.31) | ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7306837 | 0.82 | KDM4E (0.30) | KDM4E | |
| SCHEMBL11118319 | 0.81 | HRH3 (0.37) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11008990 | 0.79 | KMT2A (0.31) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL11113955 | 0.78 | KDM4E (0.35) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10375872 | 0.78 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ARAD52KDM4E | |
| SCHEMBL7306833 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ARAD52KDM4E | |
| SCHEMBL10374486 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116948-A2 | (2-Oxo-1,2,3,5-tetrahydroimidazo-(2,1-b)quinazolinyl)-oxyalkyl-amides | SYNTEX (U.S.A.) INC. (US) | 1984-08-29 | — | — | EP | disclosed |