Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113955 | 0.97 | KDM4E (0.35) | HRH3KDM4EMEN1KMT2AHTT | |
| SCHEMBL11009546 | 0.89 | KDM4E (0.39) | HRH3KDM4EMEN1KMT2AHTT | |
| SCHEMBL10376949 | 0.82 | ALDH1A1 (0.34) | HRH3KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11114380 | 0.81 | ALDH1A1 (0.34) | HRH3KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11116583 | 0.79 | ALDH1A1 (0.36) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10374571 | 0.78 | PDE3B (0.38) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10376947 | 0.77 | KDM4E (0.38) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10376946 | 0.77 | HRH3 (0.37) | HRH3KDM4EMEN1KMT2AHTT | |
| SCHEMBL11008698 | 0.77 | ALDH1A1 (0.34) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL10377030 | 0.77 | KDM4E (0.37) | KDM4EMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116948-A2 | (2-Oxo-1,2,3,5-tetrahydroimidazo-(2,1-b)quinazolinyl)-oxyalkyl-amides | SYNTEX (U.S.A.) INC. (US) | 1984-08-29 | — | — | EP | disclosed |