Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368699 | 0.89 | MCHR1 (0.56) | MCHR1ALDH1A1KDM4EKMT2A | |
| SCHEMBL10372576 | 0.87 | FFAR1 (0.59) | SIGMAR1ALDH1A1DRD4KMT2A | |
| SCHEMBL4229644 | 0.81 | SMN1; SMN2 (0.60) | ALDH1A1KDM4ECCR3KMT2APOLB | |
| SCHEMBL10372974 | 0.81 | MCHR1 (0.48) | MCHR1ALDH1A1KDM4EDRD4POLB | |
| SCHEMBL10371173 | 0.81 | LMNA (0.52) | SIGMAR1MCHR1ALDH1A1KDM4EDRD4 | |
| SCHEMBL17455957 | 0.81 | MCHR1 (0.48) | MCHR1CCR3 | |
| SCHEMBL10371219 | 0.80 | KCNH2 (0.64) | MCHR1ALDH1A1KDM4EKMT2ADRD2 | |
| SCHEMBL10371522 | 0.78 | CHRM3 (0.47) | KDM4E | |
| SCHEMBL10371598 | 0.78 | ACHE (0.53) | SIGMAR1ALDH1A1KDM4EDRD4 | |
| SCHEMBL10563762 | 0.77 | KDM4E (0.51) | SIGMAR1ALDH1A1KDM4EKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107930-A2 | Fused aromatic oxazepinones and sulphur analogues thereof and their preparation and use in counteracting histamine | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1984-05-09 | — | — | EP | disclosed |