Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | LIG1 | P18858 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809319 | 0.81 | ADRB2 (0.71) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL8972933 | 0.76 | ADRB2 (0.68) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| Hydrochloric Acid SCHEMBL11263040 | 0.76 | ADRB2 (0.54) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL10756505 | 0.75 | DRD2 (0.56) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL11554807 | 0.75 | ADRB2 (0.56) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL11150348 | 0.73 | TSHR (0.61) | ADRB2ADRB1HTR1AADRA1ASMN1; SMN2 | |
| SCHEMBL10716946 | 0.73 | ADRB2 (0.56) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| 1,2-Diallyloxybenzene SCHEMBL29768784 | 0.71 | HPGD (0.60) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| 1,2-Diallyloxybenzene SCHEMBL366516 | 0.71 | HPGD (0.60) | ADRB2ADRB1HTR1ASLC22A1LMNA | |
| SCHEMBL7924927 | 0.70 | HPGD (0.57) | ADRB2ADRB1HTR1ASLC22A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121176-A1 | Indolinone-2 derivatives, process for their preparation, medicines containing them and intermediate compounds | Roche Diagnostics GmbH (DE) | 1984-10-10 | — | — | EP | disclosed |