Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3654110 | 0.79 | SMN1; SMN2 (0.36) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 | |
| SCHEMBL6064750 | 0.78 | MEN1 (0.34) | SMN1; SMN2CHRM5CHRM3CHRM4CHRM1 | |
| SCHEMBL10237646 | 0.78 | SLC6A2 (0.33) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 | |
| SCHEMBL5779140 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 | |
| SCHEMBL9735269 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 | |
| SCHEMBL23547193 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 | |
| SCHEMBL10536758 | 0.77 | MEN1 (0.39) | SMN1; SMN2OPRD1SLC6A2SLC6A4MEN1 | |
| SCHEMBL20467165 | 0.76 | CYP1A2 (0.39) | TSHR | |
| SCHEMBL431808 | 0.76 | OPRD1 (0.36) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 | |
| Propane SCHEMBL3983224 | 0.76 | SMN1; SMN2 (0.39) | SMN1; SMN2CHRM5CHRM3OPRD1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455168-A | CONTAINING A HETEROCYCLIC, HYDROXY AMINE OR AMIDE | RICOH COMPANY, LTD. (JP) | 1984-06-19 | — | — | US | disclosed |