Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292381 | 0.80 | KDM4E (0.40) | MAPTKDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL25170534 | 0.80 | MAPT (0.48) | MAPTKDM4EMAPK1TP53ALDH1A1 | |
| SCHEMBL9814072 | 0.78 | CLCN2 (0.41) | MAPTKDM4EMAPK1TP53ALDH1A1 | |
| SCHEMBL28436581 | 0.78 | HIF1A (0.53) | MAPTKDM4EMAPK1TP53ALDH1A1 | |
| SCHEMBL3033905 | 0.77 | MAPT (0.38) | MAPTKDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL23723833 | 0.75 | KMT2A (0.42) | MAPTKDM4EMAPK1TP53ALDH1A1 | |
| SCHEMBL28056190 | 0.75 | IDO1 (0.44) | MAPTKDM4EMAPK1TP53ALDH1A1 | |
| SCHEMBL14339474 | 0.74 | KDM4E (0.50) | MAPTKDM4EMAPK1ALDH1A1LMNA | |
| SCHEMBL9645369 | 0.72 | MAPT (0.38) | MAPTKDM4EMAPK1TP53ALDH1A1 | |
| SCHEMBL7528395 | 0.72 | AMY1A (0.39) | MAPTKDM4EMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109817-A2 | Process for preparing oxazolinoazetidinones | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |