Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69364 | 0.84 | MAPT (0.48) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL9335491 | 0.82 | MAPK1 (0.46) | CLCN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL28436581 | 0.82 | HIF1A (0.53) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| Pentachlorophenol SCHEMBL7590198 | 0.81 | MAPK1 (0.41) | CLCN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL23723833 | 0.78 | KMT2A (0.42) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL28056190 | 0.78 | IDO1 (0.44) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL23723768 | 0.78 | ALDH1A1 (0.41) | MAPTMAPK1ALDH1A1HPGDKDM4E | |
| SCHEMBL11114571 | 0.78 | MAPT (0.39) | CLCN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL30715275 | 0.78 | ALDH1A1 (0.46) | CLCN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL53547 | 0.78 | ALDH1A1 (0.46) | CLCN2MAPTMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299890-B1 | PROCESS FOR THE CHLORINATION OF PHENOLIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1991-12-11 | — | — | EP | claimed |
| EP-0283411-B1 | PROCESS FOR CHLORINATING PHENOLIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1991-08-07 | — | — | EP | claimed |
| EP-0255452-B1 | PROCESS FOR CHLORINATING PHENOLIC COMPOUNDS | RHONE-POULENC CHIMIE (FR) | 1990-01-24 | — | — | EP | claimed |
| US-4885408-A | USING GASEOUS CHLORINE IN PRESENCE OF LEWIS ACIDS | RHONE-POULENC CHIMIE (FR) | 1989-12-05 | — | — | US | claimed |
| US-4855513-A | Chlorination of phenolic compounds | RHONE-POULENC CHIMIE (FR) | 1989-08-08 | — | — | US | claimed |
| US-4954662-A | Selective chlorination of ortho-substituted phenols | RHONE-POULENC CHIMIE (FR) | 1990-09-04 | — | — | US | disclosed |
| US-4885408-A | USING GASEOUS CHLORINE IN PRESENCE OF LEWIS ACIDS | RHONE-POULENC CHIMIE (FR) | 1989-12-05 | — | — | US | disclosed |
| US-4855513-A | Chlorination of phenolic compounds | RHONE-POULENC CHIMIE (FR) | 1989-08-08 | — | — | US | disclosed |