⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458546 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11354270 | 0.97 | — | — | |
| SCHEMBL31197220 | 0.83 | — | — | |
| Ethoxycarbonyl Group SCHEMBL27884569 | 0.78 | UHRF1 (0.37) | — | |
| SCHEMBL6506836 | 0.77 | MAPK14 (0.58) | — | |
| SCHEMBL20872889 | 0.77 | CCR1 (0.65) | — | |
| SCHEMBL14770762 | 0.75 | IDO1 (0.44) | — | |
| SCHEMBL44068 | 0.72 | — | — | |
| SCHEMBL29397106 | 0.72 | CCR1 (1.00) | — | |
| SCHEMBL4027001 | 0.72 | IDO1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2204 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986271-A | Cell cycle regulator, and pharmaceutical preparation and application thereof | 贵州大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117229202-B | Preparation method of intermediate of BRD9 targeted degradation compound | 苏州美诺医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-117229202-A | Preparation method of intermediate of BRD9 targeted degradation compound | 苏州美诺医药科技有限公司 | 2023-12-15 | — | — | CN | claimed |
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | claimed |
| EP-3728237-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | claimed |
| EP-3728235-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | Syngenta Crop Protection AG (CH) | 2020-10-28 | — | — | EP | claimed |
| EP-3728237-A1 | SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | Syngenta Crop Protection AG (CH) | 2020-10-28 | — | — | EP | claimed |
| EP-3728214-A1 | SUBSTITUTED N-HETEROCYCLYL- AND N-HETEROARYL-TETRAHYDROPYRIMIDINONES AND THE SALTS THEREOF, AND THE USE OF SAME AS HERBICIDAL ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2020-10-28 | — | — | EP | claimed |
| WO-2020002090-A1 | SUBSTITUTED THIAZOLYLPYRROLONES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | claimed |
| WO-2020002091-A1 | SUBSTITUTED THIAZOLYLPYRROLONES, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-01-02 | — | — | WO | claimed |
| CN-104945378-A | Compounds for the treatment of premature aging and especially premature aging | ABIVAX | 2015-09-30 | — | — | CN | claimed |
| CN-103153963-B | Cyclopropane compounds | EISAI R&D MAN CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-102898264-B | Catalytic preparation process for aromatic nitrile or heteroaromatic nitrile | UNIV ZHEJIANG | 2014-07-02 | — | — | CN | claimed |
| EP-2426106-B1 | Piperidine and Piperazine derivatives for the treatment of tumours | MERCK PATENT GMBH (DE) | 2013-07-31 | — | — | EP | claimed |
| CN-103153963-A | Cyclopropane compounds | EISAI R&D MAN CO LTD | 2013-06-12 | — | — | CN | claimed |
| CN-102304082-B | Synthesis method of 2-chloro-4-(piperidylmethyl)pyridine | UNIV CHANGZHOU | 2013-05-22 | — | — | CN | claimed |
| CN-102304082-A | Synthesis method of 2-chloro-4-(piperidylmethyl)pyridine | UNIV CHANGZHOU | 2012-01-04 | — | — | CN | claimed |
| CN-102199172-A | Method for preparing 1-substituted phosphorus dichloride | KINGCHEM DALIAN PHARMA SCIENCE CO LTD | 2011-09-28 | — | — | CN | claimed |
| US-6759428-B2 | SUCH AS N-((1,2)-2-(((CYANO(CYCLOPROPYL)METHYL)AMINO)CARBONYL) CYCLOHEXYL)-1H-INDOLE-2-CARBOXAMIDE; CATHEPSIN K INHIBITORS | ROCHE PALO ALTO LLC | 2004-07-06 | — | — | US | claimed |
| US-20040077646-A1 | Indole nitriles | ROCHE PALO ALTO LLC | 2004-04-22 | — | — | US | claimed |