SCHEMBL14770762

SCHEMBL14770762

Cc1ccc(-c2ccnc(Cl)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.44
FDPS P14324 1/20 0.44
DYRK1A Q13627 1/20 0.43
CCNC P24863 1/20 0.42
CDK8 P49336 1/20 0.42
S1PR1 P21453 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP11 Q9NR21 1/20 0.41
MAPK14 Q16539 2/20 0.40
MAPKAPK2 P49137 1/20 0.40
KMT2A Q03164 2/20 0.40
POLB P06746 1/20 0.40
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40
PLAT P00750 1/20 0.40
RECQL P46063 1/20 0.39
LOX P28300 1/20 0.39
LOXL3 P58215 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
MAPK13 O15264 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4027001 0.84 IDO1 (0.55) IDO1CCNCCDK8S1PR1PARP10
SCHEMBL3500189 0.83 MAP4K4 (0.49) IDO1CCNCCDK8S1PR1MAPKAPK2
SCHEMBL13453334 0.82 MAPK14 (0.44) IDO1S1PR1PARP10PARP11MAPK14
SCHEMBL25070215 0.81 ADORA2A (0.54) IDO1CCNCCDK8PLAUTDP1
SCHEMBL4672168 0.80 LMNA (0.52) IDO1DYRK1ACCNCCDK8S1PR1
SCHEMBL6506836 0.80 MAPK14 (0.58) IDO1MAPK14
SCHEMBL31380443 0.80 ROCK2 (0.45) IDO1CCNCCDK8MAPK14RECQL
SCHEMBL4903193 0.80 ROCK2 (0.45) IDO1CCNCCDK8MAPK14RECQL
SCHEMBL28163101 0.79 CCNC (0.46) IDO1DYRK1ACCNCCDK8S1PR1
SCHEMBL12050763 0.79 ESR2 (0.47) IDO1CCNCCDK8MAPKAPK2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708063-A Phenoxy coordinated fluorine-containing N/C/N/O tetradentate metal platinum (II) complex and application thereof 浙江工业大学 2025-03-28 CN disclosed
CN-111362984-A Compounds, devices, and formulations related to iridium complexes with aza-benzo fused ligands 环球展览公司 2020-07-03 CN disclosed
CN-111303212-A Compounds, devices, and formulations related to iridium complexes with aza-benzo fused ligands 环球展览公司 2020-06-19 CN disclosed
EP-3000816-B1 A FIRST DEVICE COMPRISING IRIDIUM COMPLEXES WITH AZA-BENZO FUSED LIGANDS UNIVERSAL DISPLAY CORP (US) 2017-12-20 EP disclosed
EP-3000816-B1 A FIRST DEVICE COMPRISING IRIDIUM COMPLEXES WITH AZA-BENZO FUSED LIGANDS UNIVERSAL DISPLAY CORP (US) 2017-12-20 EP disclosed
EP-3000816-A1 A FIRST DEVICE COMPRISING IRIDIUM COMPLEXES WITH AZA-BENZO FUSED LIGANDS Universal Display Corporation (US) 2016-03-30 EP disclosed
EP-3000816-A1 A FIRST DEVICE COMPRISING IRIDIUM COMPLEXES WITH AZA-BENZO FUSED LIGANDS Universal Display Corporation (US) 2016-03-30 EP disclosed
EP-2730583-B1 Iridium complexes with aza-benzo fused ligands UNIVERSAL DISPLAY CORP (US) 2016-01-13 EP disclosed
EP-2730583-B1 Iridium complexes with aza-benzo fused ligands UNIVERSAL DISPLAY CORP (US) 2016-01-13 EP disclosed
US-8946697-B1 Iridium complexes with aza-benzo fused ligands UNIVERSAL DISPLAY CORPORATION (US) 2015-02-03 US disclosed
US-8946697-B1 Iridium complexes with aza-benzo fused ligands UNIVERSAL DISPLAY CORPORATION (US) 2015-02-03 US disclosed
US-8946697-B1 Iridium complexes with aza-benzo fused ligands UNIVERSAL DISPLAY CORPORATION (US) 2015-02-03 US disclosed
CN-103804426-A Compounds, devices, and formulations related to iridium complexes with aza-benzo fused ligands UNIVERSAL DISPLAY CORP 2014-05-21 CN disclosed
EP-2730583-A1 Iridium complexes with aza-benzo fused ligands Universal Display Corporation (US) 2014-05-14 EP disclosed
EP-2730583-A1 Iridium complexes with aza-benzo fused ligands Universal Display Corporation (US) 2014-05-14 EP disclosed
US-20130065880-A1 COMPOUNDS AS TYROSINE KINASE MODULATORS ALLERGAN, INC. (US) 2013-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130065880-A1 COMPOUNDS AS TYROSINE KINASE MODULATORS ABL1, ERBB2, LCK IDO1 1594/4885FDPS 1518/4885DYRK1A 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.