Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15881317 | 0.77 | GRM5 (0.48) | SORT1L3MBTL1RXFP1LMNAPOLB | |
| SCHEMBL10854771 | 0.74 | AURKA (0.47) | SORT1L3MBTL1ATMPOLBALDH1A1 | |
| SCHEMBL11341693 | 0.73 | HRH4 (0.53) | — | |
| SCHEMBL18989942 | 0.70 | SORD (0.42) | SORT1L3MBTL1RXFP1POLBAURKA | |
| SCHEMBL27690700 | 0.70 | MALT1 (0.36) | MALT1 | |
| SCHEMBL24714802 | 0.69 | CYP1A2 (0.49) | L3MBTL1ATMLMNAPOLBCYP1A2 | |
| SCHEMBL30861989 | 0.69 | CTSK (0.49) | SORT1L3MBTL1RXFP1LMNAPOLB | |
| SCHEMBL11303883 | 0.69 | — | — | |
| SCHEMBL3296292 | 0.69 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL30407284 | 0.69 | CYP3A4 (0.41) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0100795-A1 | Selected 2-trichloromethyl-4-pyrimidinyl carbamates and their use as fungicides | OLIN CORPORATION (US) | 1984-02-22 | — | — | EP | disclosed |