Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Carbromal. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbromal SCHEMBL1537493 | 0.95 | CRBN (0.32) | — | |
| Carbromal SCHEMBL620919 | 0.93 | CRBN (0.33) | — | |
| Carbromal SCHEMBL9262322 | 0.91 | CRBN (0.34) | — | |
| Carbromal SCHEMBL7266759 | 0.91 | CRBN (0.34) | — | |
| Carbromal SCHEMBL1328002 | 0.91 | CRBN (0.34) | — | |
| Carbromal SCHEMBL7031146 | 0.90 | CRBN (0.33) | — | |
| Carbromal SCHEMBL4183308 | 0.88 | CRBN (0.32) | — | |
| Carbromal SCHEMBL11414078 | 0.88 | CRBN (0.37) | — | |
| Carbromal SCHEMBL2025221 | 0.88 | CRBN (0.37) | — | |
| Carbromal SCHEMBL1537494 | 0.88 | CRBN (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452876-A | NON-MIGRATING ACID STABILIZING AGENT IN LIGHT SENSITIVE LAYER | INTERNATIONAL DIAZO CHAPEL & CIE, A FRENCH BODY CORPORATE (FR) | 1984-06-05 | — | — | US | disclosed |