Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 2/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059198 | 0.83 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL11118344 | 0.82 | SCN1A (0.44) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 | |
| SCHEMBL11113049 | 0.77 | ACACB (0.43) | ACACB | |
| SCHEMBL11114790 | 0.76 | CYP1A2 (0.45) | ALDH1A1CYP3A4SCN1ASCN2ASCN3A | |
| SCHEMBL11110055 | 0.71 | ALDH1A1 (0.45) | ALDH1A1CYP3A4LMNACYP1A2TSHR | |
| SCHEMBL11112280 | 0.71 | ACACB (0.41) | ALDH1A1ACACBATM | |
| SCHEMBL11115793 | 0.71 | ACACB (0.40) | CHRM2CHRM1CHRM3ACACB | |
| SCHEMBL10686879 | 0.68 | MAPT (0.46) | CHRM2CHRM1CHRM3ALDH1A1CYP3A4 | |
| SCHEMBL5132689 | 0.65 | MAPT (0.48) | ALDH1A1CYP3A4LMNACYP1A2CYP2D6 | |
| SCHEMBL8399137 | 0.65 | CHRM2 (0.47) | CHRM2CHRM1CHRM4CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |