Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.31 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850143 | 0.70 | — | — | |
| SCHEMBL13034810 | 0.68 | ALOX5AP (0.33) | — | |
| SCHEMBL13034822 | 0.68 | ALOX5AP (0.33) | — | |
| SCHEMBL11115022 | 0.68 | GRIN2D (0.32) | — | |
| SCHEMBL10849044 | 0.66 | HSD11B1 (0.33) | — | |
| SCHEMBL18220553 | 0.64 | ALOX5AP (0.30) | — | |
| SCHEMBL19459385 | 0.61 | — | — | |
| SCHEMBL29359899 | 0.58 | GRIN2D (0.39) | SLC22A2SLC47A1MAPT | |
| SCHEMBL13779596 | 0.58 | — | — | |
| SCHEMBL13779594 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116276-A2 | Derivatives of spirocyclic amino-acids, their process of preparation, agents containing them, and their use, as well as spirocyclic amino-acids as intermediaries and their process of preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-22 | — | — | EP | disclosed |