Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799678 | 0.64 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL25757 | 0.60 | — | — | |
| SCHEMBL2965730 | 0.59 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL498016 | 0.59 | — | — | |
| SCHEMBL9770023 | 0.58 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL394300 | 0.58 | TAAR1 (0.76) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL297554 | 0.57 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11974592 | 0.56 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11974601 | 0.56 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL11974593 | 0.56 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110280-A1 | Process for the production of penem compounds | SCHERING CORPORATION (US) | 1984-06-13 | — | — | EP | disclosed |