Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.61 |
| ▸ | DRD2 | P14416 | 8/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 6/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11114697 | 0.99 | DRD3 (0.60) | DRD3DRD2ADRA1AFAAHCNR1 | |
| SCHEMBL11118107 | 0.98 | DRD3 (0.64) | DRD3DRD2ADRA1AFAAHCNR1 | |
| SCHEMBL11114775 | 0.93 | DRD3 (0.51) | DRD3DRD2ADRA1AFAAHCNR1 | |
| SCHEMBL11118618 | 0.90 | DRD3 (0.53) | DRD3DRD2ADRA1AFAAHCNR1 | |
| SCHEMBL11114822 | 0.89 | DRD2 (0.57) | DRD3DRD2ADRA1AFAAHCNR1 | |
| SCHEMBL11114098 | 0.85 | HRH3 (0.50) | — | |
| SCHEMBL11113046 | 0.85 | HRH3 (0.50) | — | |
| SCHEMBL11116160 | 0.82 | DRD3 (0.77) | DRD3DRD2ADRA1AFAAHCNR1 | |
| SCHEMBL11118198 | 0.81 | HRH3 (0.46) | — | |
| SCHEMBL11118155 | 0.80 | DRD3 (0.65) | DRD3DRD2FAAHCNR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |