SCHEMBL11115445

SCHEMBL11115445

NNS(=O)(=O)Oc1ccc2ccccc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.65
CA2 P00918 3/20 0.65
CA9 Q16790 2/20 0.65
L3MBTL1 Q9Y468 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
LMNA P02545 2/20 0.50
PPARG P37231 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
GAA P10253 2/20 0.46
MAPK1 P28482 1/20 0.46
CA12 O43570 1/20 0.44
AGXT P21549 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2A6 P11509 1/20 0.44
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41
RCE1 Q9Y256 1/20 0.41
GPR84 Q9NQS5 1/20 0.41
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11112160 0.92 CA2 (0.52) CA1CA2CA9L3MBTL1TDP1
SCHEMBL187752 0.80 CA1 (0.59) CA1CA2CA9PPARGMEN1
SCHEMBL9750123 0.79 CA2 (1.00) CA1CA2CA9L3MBTL1TDP1
SCHEMBL31194960 0.79 CA2 (1.00) CA1CA2CA9L3MBTL1TDP1
SCHEMBL8320952 0.78 CA1 (0.70) CA1CA2CA9L3MBTL1TDP1
SCHEMBL20768536 0.78 KMT2A (0.60) CA1CA2CA9TDP1LMNA
SCHEMBL148404 0.76 LMNA (0.46) CA1CA2CA9LMNAHTT
SCHEMBL38659523 0.76 KMT2A (0.58) CA1CA2CA9TDP1LMNA
Ammonia Solution, Strong SCHEMBL28551491 0.76 KMT2A (0.58) CA1CA2CA9TDP1LMNA
SCHEMBL7291218 0.75 CA1 (0.66) CA1CA2CA9L3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0129182-A1 Arylsulfonyl hydrazones as blowing agents BAYER AG (DE) 1984-12-27 EP disclosed