Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 6/20 | 0.58 |
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965414 | 0.85 | ALPL (0.52) | HSD17B3ALPLALPIERAP1NPSR1 | |
| SCHEMBL10791803 | 0.81 | HSD17B3 (0.62) | HSD17B3ALPLALPIERAP1MAOA | |
| SCHEMBL10791689 | 0.79 | HSD17B3 (0.56) | HSD17B3ALPLALPIERAP1NPSR1 | |
| SCHEMBL10846458 | 0.78 | HSD17B3 (0.70) | HSD17B3ERAP1NPSR1RXFP1KDM4E | |
| SCHEMBL10850744 | 0.78 | ALPL (0.84) | ALPLALPIMAOAMAOB | |
| SCHEMBL10847031 | 0.78 | HSD17B3 (0.84) | HSD17B3ERAP1NPSR1RXFP1KDM4E | |
| SCHEMBL591899 | 0.76 | HSD17B3 (1.00) | HSD17B3ERAP1NPSR1RXFP1KDM4E | |
| SCHEMBL31366988 | 0.76 | HSD17B3 (1.00) | HSD17B3ERAP1NPSR1RXFP1KDM4E | |
| SCHEMBL959613 | 0.76 | HSD17B3 (0.64) | HSD17B3ERAP1NPSR1KDM4EGLA | |
| SCHEMBL5957207 | 0.75 | HSD17B3 (0.79) | HSD17B3ERAP1NPSR1RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |