Phenylglyoxal

Phenylglyoxal

SCHEMBL11116049

O=CC(=O)c1ccccc1.c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
MAPK1 P28482 2/20 1.00
AKT1 P31749 1/20 0.61
NFE2L2 Q16236 1/20 0.58
MAPT P10636 4/20 0.54
RECQL P46063 3/20 0.54
PLIN1 O60240 2/20 0.54
LMNA P02545 2/20 0.54
PLIN5 Q00G26 2/20 0.54
ABHD5 Q8WTS1 2/20 0.54
BCHE P06276 1/20 0.54
TNFRSF1A P19438 1/20 0.54
ACHE P22303 1/20 0.54
MAOB P27338 1/20 0.54
CYP1B1 Q16678 1/20 0.54
CES1 P23141 3/20 0.52
CES2 O00748 2/20 0.52
TSHR P16473 2/20 0.52
DAO P14920 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylglyoxal SCHEMBL16745575 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL5716642 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL57493 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL27658895 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL10994854 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL141911 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL8015710 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL1308120 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL28894210 0.95 ALDH1A1 (0.90) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL28340057 0.95 ALDH1A1 (0.90) ALDH1A1TDP1MAPK1AKT1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4451556-A Tellurium imaging composition including base ENERGY CONVERSION DEVICES, INC. (US) 1984-05-29 US claimed
EP-0098018-A2 Imaging film and composition employing an organo-metallic compound and method for recording electromagnetic radiation ENERGY CONVERSION DEVICES, INC. (US) 1984-01-11 EP claimed
US-4340662-A PHOTOSENSITIVE FILMS ENERGY CONVERSION DEVICES, INC. (US) 1982-07-20 US claimed
US-4281058-A A PHOTOSENSITIVE COMPLEX OF THE TELLURIUM COMPOUND AND A GLYCEROL ETHER OR THIOETHER; NONSILVER PHOTOGRAPHY ENERGY CONVERSION DEVICES, INC. (US) 1981-07-28 US claimed