Phenylglyoxal

Phenylglyoxal

SCHEMBL57493

O=CC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
MAPK1 P28482 2/20 1.00
AKT1 P31749 1/20 0.61
NFE2L2 Q16236 1/20 0.58
MAPT P10636 4/20 0.54
RECQL P46063 3/20 0.54
PLIN1 O60240 2/20 0.54
LMNA P02545 2/20 0.54
PLIN5 Q00G26 2/20 0.54
ABHD5 Q8WTS1 2/20 0.54
BCHE P06276 1/20 0.54
TNFRSF1A P19438 1/20 0.54
ACHE P22303 1/20 0.54
MAOB P27338 1/20 0.54
CYP1B1 Q16678 1/20 0.54
CES1 P23141 3/20 0.52
CES2 O00748 2/20 0.52
TSHR P16473 2/20 0.52
DAO P14920 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylglyoxal SCHEMBL16745575 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL5716642 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL11116049 1.00 ALDH1A1 (1.00) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL27658895 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL10994854 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL141911 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL8015710 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL1308120 0.97 ALDH1A1 (0.95) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL28894210 0.95 ALDH1A1 (0.90) ALDH1A1TDP1MAPK1AKT1NFE2L2
Phenylglyoxal SCHEMBL28340057 0.95 ALDH1A1 (0.90) ALDH1A1TDP1MAPK1AKT1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13281 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115532062-B Enhanced chlorine-resistant reverse osmosis membrane and preparation method thereof Hunan Aowui Membrane Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-20250369981-A1 Phenylglyoxal-Based Alkyne (PGA) Chemical Tag for Protein Citrullination Analysis WISCONSIN ALUMNI RES FOUND (US) 2025-12-04 US claimed
US-12460257-B2 Methods for detecting RNA binding protein complexes ECLIPSE BIOINNOVATIONS, INC. (US) 2025-11-04 US claimed
CN-115754296-B Self-assembled DNA nucleic acid chain sensor-based chemiluminescence rapid detection method for multiple tumor markers 南昌大学 2025-05-30 CN claimed
CN-115927146-B Genetically engineered bacterium for synthesizing natural benzaldehyde and derivatives thereof and application of genetically engineered bacterium 上海光玥生物科技有限公司 2025-05-16 CN claimed
CN-119970596-A Composition with whitening and skin tendering effects, essence emulsion, and preparation method and application thereof 麦吉丽生物科技有限公司 2025-05-13 CN claimed
EP-4548097-A1 IMMUNOASSAY USING CARBON NANOMATERIALS AND METHOD OF DETECTING TARGET ANTIGEN USING THE SAME Lee, Ji Hoon (US) 2025-05-07 EP claimed
CN-119925246-A Composition with effects of controlling oil, removing acnes and astringing pores, skin care product and preparation method thereof 湖北省吉美化妆品有限公司 2025-05-06 CN claimed
US-20250136445-A1 HYDROGEN PEROXIDE MANUFACTURING PROCESS AND MANUFACTURING SYSTEM BASED ON PHOTOCHEMICAL REACTION KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-05-01 US claimed
US-12286487-B2 Antibody compounds with reactive arginine and related antibody drug conjugates UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-04-29 US claimed
EP-0005848-B1 N-ALKYLATED AMINOALCOHOLS AND THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1981-12-30 EP claimed
EP-0038060-A1 A pharmaceutical composition for treating hypertension containing L-alpha-methyl-3,4-dihydroxyphenylalanine and salicylamide MERCK & CO. INC. (US) 1981-10-21 EP claimed
EP-0030174-A1 Piperidylbenzimidazolinone derivatives, process for their preparation and pharmaceutical compositions containing them SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) 1981-06-10 EP claimed
EP-0008653-A1 N-substituted benzimidazoles, processes for their preparation and medicines containing them C.H. BOEHRINGER SOHN (DE) 1980-03-19 EP claimed
EP-0008259-A1 Piperidyl-benzimidazolinone derivatives, processes for their preparation and pharmaceutical compositions containing them SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) 1980-02-20 EP claimed
US-4167415-A Photocurable composition comprising copolymer of maleic acid monoester and α-olefin compound KANSAI PAINT CO., LTD. (JP) 1979-09-11 US claimed
US-4166180-A 2-ARYLPIPERAZINE DERIVATIVES AND THE PREPARATION THEREOF HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1979-08-28 US claimed
US-4092172-A Photocurable composition comprising a copolymer of a maleic acid monoester with an α-olefine KANSAI PAINT CO., LTD. (JA) 1978-05-30 US claimed
US-4079180-A FROM CEPHALOSPORIN C AND AN ALPHA-KETO DERIVATIVE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-03-14 US claimed
US-3954584-A Photopolymerizable vinylurethane liquid composition KANSAI PAINT COMPANY (JA) 1976-05-04 US claimed