Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2164910 | 0.82 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL8023138 | 0.82 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL19010425 | 0.82 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL6692168 | 0.80 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL29315763 | 0.80 | KDM4E (0.51) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL4969 | 0.80 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL2924557 | 0.80 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2KMT2ATDP1L3MBTL1 | |
| SCHEMBL6687442 | 0.79 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL9097812 | 0.78 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 | |
| SCHEMBL8434592 | 0.78 | SIGMAR1 (0.54) | ALDH1A1SMN1; SMN2KMT2ASIGMAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |