Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111322 | 0.92 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4EMAPTCACNA1C | |
| SCHEMBL11114191 | 0.89 | CACNA1C (0.53) | KMT2AALDH1A1KDM4EMAPTCACNA1C | |
| SCHEMBL9838777 | 0.89 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4EMAPTCACNA1C | |
| SCHEMBL9691243 | 0.87 | ALDH1A1 (0.46) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11168071 | 0.83 | KDM4E (0.43) | KMT2AALDH1A1KDM4EMAPTCACNA1C | |
| SCHEMBL10926570 | 0.82 | MEN1 (0.49) | KMT2AALDH1A1KDM4EMAPTCACNA1C | |
| SCHEMBL11117972 | 0.82 | NR1I2 (0.45) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL11369478 | 0.81 | CYP1A2 (0.60) | KMT2AALDH1A1KDM4EMAPTCACNA1C | |
| SCHEMBL9691573 | 0.79 | ALDH1A1 (0.44) | KMT2AALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL31069036 | 0.79 | MAPT (0.69) | KMT2AALDH1A1KDM4EMAPTCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111453-A1 | Amide derivatives | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |