Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110302 | 0.92 | NR1I2 (0.53) | NR1I2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11116700 | 0.89 | NR1I2 (0.48) | NR1I2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL11126649 | 0.87 | NR1I2 (0.48) | NR1I2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL9691243 | 0.87 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTRAB9ALMNA | |
| SCHEMBL11168071 | 0.84 | KDM4E (0.43) | ALDH1A1KDM4EMAPTKMT2ATSHR | |
| SCHEMBL11116098 | 0.82 | KMT2A (0.44) | NR1I2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL7095670 | 0.81 | ALDH1A1 (0.50) | NR1I2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL16415757 | 0.80 | NR1I2 (0.69) | NR1I2ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL9691573 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTRAB9ALMNA | |
| SCHEMBL10775020 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111455-A2 | Unsaturated lactones | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | claimed |
| EP-0111455-A2 | Unsaturated lactones | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |