SCHEMBL11116485

SCHEMBL11116485

COC(=O)C(C)CCOCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.48
HTT P42858 1/20 0.48
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 1/20 0.45
ESRRB O95718 1/20 0.45
KMT2A Q03164 1/20 0.44
FOLH1 Q04609 1/20 0.44
CTSB P07858 1/20 0.43
TSHR P16473 2/20 0.43
MIF P14174 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12539606 0.89 ALDH1A1 (0.51) SMN1; SMN2HTTALDH1A1CYP2C19L3MBTL1
SCHEMBL20180715 0.86 TSHR (0.49) SMN1; SMN2HTTALDH1A1CYP2C19L3MBTL1
SCHEMBL20180695 0.86 TSHR (0.49) SMN1; SMN2HTTALDH1A1CYP2C19L3MBTL1
SCHEMBL19746095 0.86 TSHR (0.49) SMN1; SMN2HTTALDH1A1CYP2C19L3MBTL1
SCHEMBL20180712 0.86 L3MBTL1 (0.51) SMN1; SMN2HTTALDH1A1CYP2C19HSD17B10
SCHEMBL23620881 0.86 L3MBTL1 (0.51) SMN1; SMN2HTTALDH1A1CYP2C19HSD17B10
SCHEMBL20180360 0.86 L3MBTL1 (0.51) SMN1; SMN2HTTALDH1A1CYP2C19HSD17B10
SCHEMBL18263766 0.85 HTT (0.48) SMN1; SMN2HTTALDH1A1CYP2C9CYP2C19
SCHEMBL18263742 0.85 HTT (0.48) SMN1; SMN2HTTALDH1A1CYP2C9CYP2C19
SCHEMBL11120621 0.85 HTT (0.48) SMN1; SMN2HTTALDH1A1CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed
US-4461835-A RESOLVING ARYLOXY-A-ALKYL ESTERS TO MAKE VITAMIN E INTERMEDIATES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1984-07-24 US disclosed