Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14486902 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNAKMT2A | |
| SCHEMBL16526249 | 0.76 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL10403095 | 0.74 | GAA (0.33) | ALDH1A1KMT2A | |
| SCHEMBL10972824 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNA | |
| SCHEMBL18723029 | 0.68 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10972448 | 0.68 | TDP1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL8445215 | 0.63 | — | — | |
| SCHEMBL11118817 | 0.60 | ALDH1A1 (0.64) | ALDH1A1LMNA | |
| SCHEMBL8677790 | 0.58 | — | — | |
| SCHEMBL2739417 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |