Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361580 | 0.80 | ALDH1A1 (0.36) | GAASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11362710 | 0.79 | ALDH1A1 (0.33) | GAAALDH1A1RECQLHSD17B10 | |
| SCHEMBL29089456 | 0.71 | NPC1 (0.46) | GAASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL15017837 | 0.68 | TP53 (0.40) | SMN1; SMN2RAB9AMEN1KMT2ARECQL | |
| SCHEMBL29089455 | 0.67 | RAB9A (0.44) | GAASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL29089447 | 0.67 | USP2 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL29089425 | 0.67 | LMNA (0.46) | GAASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL10404418 | 0.66 | ALDH1A1 (0.53) | GAASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL29089432 | 0.64 | GSK3B (0.48) | GAARAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL29089409 | 0.64 | GSK3B (0.46) | GAARAB9ANPC1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |