Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262228 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL1261782 | 1.00 | LMNA (0.54) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL1262385 | 0.98 | LMNA (0.50) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL1261857 | 0.91 | — | — | |
| SCHEMBL27476110 | 0.88 | LMNA (0.48) | LMNAMAPTSPHK1TSHRSMPD1 | |
| SCHEMBL31436265 | 0.88 | LMNA (0.48) | LMNAMAPTSPHK1TSHRSMPD1 | |
| SCHEMBL6275484 | 0.86 | LMNA (0.46) | LMNAMAPTSPHK1TSHRSMPD1 | |
| SCHEMBL11024389 | 0.84 | LMNA (0.56) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL4076477 | 0.84 | LMNA (0.56) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL29757133 | 0.84 | LMNA (0.44) | LMNAMAPTSPHK1TSHRSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457785-A | AQUEOUS DISPERSION, NONIONIC AND CATIONIC SURFACTANTS | PPG INDUSTRIES, INC. (US) | 1984-07-03 | — | — | US | disclosed |