Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CETP | P11597 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024389 | 1.00 | LMNA (0.56) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL4057586 | 0.91 | LMNA (0.52) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL8468112 | 0.90 | ALDH1A1 (0.48) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL27303340 | 0.89 | LMNA (0.50) | LMNAMAPTMAPK1CYP2D6SPHK1 | |
| SCHEMBL28862599 | 0.88 | ALDH1A1 (0.56) | LMNAMAPTMAPK1SPHK1GMNN | |
| Ethylene Glycol SCHEMBL23391391 | 0.86 | LMNA (0.50) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL7875772 | 0.86 | LMNA (0.50) | LMNAMAPTCYP2D6SPHK1GMNN | |
| SCHEMBL7875780 | 0.86 | LMNA (0.50) | LMNAMAPTCYP2D6SPHK1GMNN | |
| Ethylene Glycol SCHEMBL4353876 | 0.86 | LMNA (0.50) | LMNAMAPTCYP2D6SPHK1GMNN | |
| Ethylene Glycol SCHEMBL23391403 | 0.86 | LMNA (0.50) | LMNAMAPTCYP2D6SPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108419431-A | Cosmetic containing multilayer nanoparticles encapsulating natural poorly-soluble drug as antiseptic substance and method for producing same | 郑汉洙 | 2018-08-17 | — | — | CN | disclosed |
| EP-1392241-B1 | SYSTEM FOR OSMOTIC DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS | SUPERNUS PHARMACEUTICALS INC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1392241-A4 | SYSTEM FOR OSMOTIC DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS | SHIRE LAB INC (US) | 2006-01-25 | — | — | EP | disclosed |
| US-6838093-B2 | System for osmotic delivery of pharmaceutically active agents | SHIRE LABORATORIES, INC. (US) | 2005-01-04 | — | — | US | disclosed |
| EP-1392241-A2 | SYSTEM FOR OSMOTIC DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS | Shire Laboratories Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20030003150-A1 | System for osmotic delivery of pharmaceutically active agents | ACTIENT PHARMACEUTICALS LLC | 2003-01-02 | — | — | US | disclosed |
| WO-2002098482-A2 | SYSTEM FOR OSMOTIC DELIVERY OF PHARMACEUTICALLY ACTIVE AGENTS | SHIRE LABORATORIES, INC. (US) | 2002-12-12 | — | — | WO | disclosed |