Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062311 | 0.78 | IDO1 (0.70) | IDO1ALDH1A1MAPTAKR1C3LOXL2 | |
| SCHEMBL11115468 | 0.75 | TSHR (0.41) | IDO1TSHRMAOB | |
| SCHEMBL2265435 | 0.74 | IDO1 (0.47) | IDO1ALDH1A1MAPTLMNAAKR1C3 | |
| SCHEMBL12134062 | 0.72 | IDO1 (0.61) | IDO1ALDH1A1MAPTLMNAAKR1C3 | |
| SCHEMBL17636185 | 0.72 | IDO1 (0.61) | IDO1MAPTLMNAAKR1C3LOXL2 | |
| SCHEMBL6577663 | 0.72 | IDO1 (0.61) | IDO1ALDH1A1MAPTLMNAAKR1C3 | |
| SCHEMBL2351746 | 0.72 | IDO1 (0.72) | IDO1ALDH1A1MAPTAKR1C3LOXL2 | |
| SCHEMBL10539925 | 0.71 | HTR2A (0.46) | IDO1LMNAAKR1C3TSHRRAB9A | |
| SCHEMBL2199007 | 0.71 | HTR2A (0.49) | IDO1AKR1C3CA12CA1CA2 | |
| SCHEMBL1824998 | 0.71 | ALDH1A1 (0.50) | IDO1ALDH1A1MAPTLMNALOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046189-B1 | ISOXAZOLINO-AZOXY COMPOUNDS AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1984-01-04 | — | — | EP | disclosed |
| EP-0046189-A1 | Isoxazolino-azoxy compounds and process for their preparation | BASF Aktiengesellschaft (DE) | 1982-02-24 | — | — | EP | disclosed |