Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13785487 | 0.90 | TSHR (0.36) | TSHRDHFRIDO1CTSLCTSB | |
| SCHEMBL10942039 | 0.80 | TSHR (0.44) | TSHRDHFRIDO1AGXTCTSL | |
| SCHEMBL11116529 | 0.75 | IDO1 (0.50) | TSHRIDO1MAOB | |
| SCHEMBL16369873 | 0.72 | ALDH1A1 (0.34) | TSHRDHFRKMT2A | |
| SCHEMBL6729320 | 0.72 | TSHR (0.36) | TSHRDHFR | |
| SCHEMBL177923 | 0.71 | TSHR (0.67) | TSHRIDO1AGXTKMT2AMAOA | |
| Cyclohexane SCHEMBL8149682 | 0.69 | TSHR (0.83) | TSHRIDO1AGXTTACR1 | |
| SCHEMBL17100019 | 0.69 | TSHR (0.52) | TSHRDHFRIDO1TACR1 | |
| SCHEMBL3985723 | 0.69 | MAOA (0.44) | TSHRDHFRIDO1AGXTMAOA | |
| SCHEMBL11540623 | 0.69 | TSHR (0.41) | TSHRDHFRIDO1AGXTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046189-B1 | ISOXAZOLINO-AZOXY COMPOUNDS AND PROCESS FOR THEIR PREPARATION | BASF Aktiengesellschaft (DE) | 1984-01-04 | — | — | EP | disclosed |
| EP-0046189-A1 | Isoxazolino-azoxy compounds and process for their preparation | BASF Aktiengesellschaft (DE) | 1982-02-24 | — | — | EP | disclosed |