Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11198523 | 0.89 | MAP4K4 (0.33) | — | |
| SCHEMBL11202223 | 0.88 | TDP1 (0.31) | — | |
| SCHEMBL11345996 | 0.81 | — | — | |
| SCHEMBL11195177 | 0.79 | — | — | |
| SCHEMBL11647597 | 0.79 | ALDH1A1 (0.40) | — | |
| SCHEMBL28133239 | 0.78 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL11642883 | 0.77 | KDM4E (0.35) | — | |
| SCHEMBL11437461 | 0.75 | NLRP3 (0.36) | — | |
| SCHEMBL543197 | 0.75 | CA1 (0.36) | CA1CA2 | |
| SCHEMBL17260749 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457941-A | RETINOPATHY, NEUROPATHY, NEPHROPATHY | SYNTEX (U.S.A.) INC. (US) | 1984-07-03 | — | — | US | disclosed |
| US-4454151-A | Use of pyrrolo pyrroles in treatment of ophthalmic diseases | SYNTEX (U.S.A.) INC. (US) | 1984-06-12 | — | — | US | disclosed |
| EP-0000649-B1 | 5-SUBSTITUTED-1,2-DIHYDRO-3H-PYRROLO(1,2-A)PYRROLE-1-CARBONITRILES AND PROCESS FOR THEIR CONVERSION TO THE CORRESPONDING 1-CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1981-03-25 | — | — | EP | disclosed |
| US-4232038-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0000649-A1 | 5-substituted-1,2-dihydro-3H-pyrrolo(1,2-a)pyrrole-1-carbonitriles and process for their conversion to the corresponding 1-carboxylic acids | SYNTEX (U.S.A.) INC. (US) | 1979-02-07 | — | — | EP | disclosed |